Quality and research

ALS conducts our own research in the field of metal, element speciation and isotope analysis of clinical samples. This work has resulted in numerous scientific articles and conference papers.

Related research

Metals in urine and serum

Determination of low-abundance elements at ultra-trace levels in urine and serum

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Metals in biological tissues

Multi-elemental characterization of soft biological tissues

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Isotope testing

Isotopic analysis of the metabolically relevant transition metals Cu, Fe and Zn in human blood from vegetarians and omnivores

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  • Research - Clinical sample analysis
    Title
    Rodushkin I.,  Ruth T., Ponter C Multi-element determination in clinical samples by ICP-SMS
    Rodushkin I., Ödman F., Branth S. Multielement analysis of whole blood by HR-ICP-MS
    Rodushkin I., Ödman F. Application of ICP-SMS for elemental determination in urine
    Rodushkin I., Ödman F.Assessment of contaminations from devices used for blood sampling and storage by ICP-SMS
    Selden, A.L., Berg, P., Rodushkin, I. Cobalt biomonitoring – a useful tool in occupational health
    Rodushkin, I., Axelsson, M.D. Application of double focusing sector field ICP-MS for multielemental characterization of human hair and nails. Part I. Analytical methodology.
    Rodushkin I., Axelsson, M.D. Application of double focusing sector field ICP-MS for multielemental characterization of human hair and nails. Part II. A study of the inhabitants of northern Sweden.
    Rodushkin I., Ödman F., Olofsson, R.S., Axelsson, M.D.     Determination of 60 elements in whole blood by sector field inductively coupled plasma mass spectrometry
    Rodushkin, I., Ödman, F., Olofsson, R., Burman, E., Axelsson, M.D. Multi-element analysis of body fluids by double-focusing ICP-MS
    Rodushkin, I., Axelsson, M.D. Application of double focusing sector field ICP-MS for multielemental characterization of human hair and nails. Part III. Direct analysis by laser ablation.
    Malinovsky, D.,Rodushkin, I.,Andren, H.,Ponter,C.,Öhlander,B.,Baxter,D.C.Separation of Fe from whole blood matrix for precise isotope ratio measurements by MC-ICP-MS: a comparison of different approaches
    Engström E.,Stenberg A.,Senioukh S.,Edelbro R.,Baxter D.C.,Rodushkin I.Multi-elemental characterization of soft biological tissues by ICP-SFMS
    Rodushkin I.,Engström E.,Stenberg A, Baxter D.C.Determination of low-abundance elements at ultra-trace levels in urine and serum by ICP-SFMS
    Stenberg A., Malinovsky D., B. Öhlander, Andren H., Forsling W., Engström L-M., Wahlin A., Engström E., Rodushkin I., Baxter D.C.Measurement of iron and zinc isotopes in human whole blood: Preliminary application to the study of HFE genotypes
    Baxter D.C., Rodushkin I., Berglund I.    Methyl mercury in biological fluids by isotope dilution
    Baxter D.C., Rodushkin I., Engström E., Klockare D., Waara H.Methylmercury measurements in whole blood by isotope-dilution GC-ICPMS with 2 sample preparation methods
    Baxter D.C., Faarinen M., Österlund H., Rodushkin I., Christensen M.Serum/plasma methylmercury determination by isotope dilution gas chromatography – inductively coupled plasma mass spectrometry
    Van Heghe L., Engström E., Rodushkin I., Cloquet C., Vanhaecke F.Isotopic analysis of the metabolically relevant transition metals Cu, Fe and Zn in human blood from vegetarians and omnivores using multi-collector ICP-mass spectrometry

Ensuring high-quality analysis

Our metal analysis laboratory in Luleå, Sweden, is equipped to perform metals analysis of clinical samples for clinical and non-clinical studies as well as routine testing. Our ISO/EN 17025 accreditation covers blood, urine, serum/plasma and other bodily fluids of both human and animal origin. In addition to our analytical services, we also offer method development, validation, method transfer and cross-validation services.

Our laboratory complies with international quality standards including:

We actively participate in interlaboratory comparisons related to analysis of clinical sample matrices. Click here to find the relevant quality documentation (new window) .

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